Forskolin is a compound found in Coleus forskohlii, a tropical plant in the mint family. The plant is native to India, and grows wild in numerous countries in Southeast Asia. It’s been used since ancient times to treat asthma, bronchitis, constipation, heart problems along with other conditions. However, it became far more well-known in 2014 after Dr. Oz praised it as a “miracle” weight loss pill.
Forskolin is sold as being an over-the-counter supplement usually containing 10-20% forskolin extract (known as pure forskolin). Manufacturers declare that it suppresses appetite so it helps with weight-loss. Summary: Forskolin is a compound found in the tropical plant Coleus forskohlii, a member of the mint family. It’s been used since the past to treat various ailments, and is also now marketed and sold as a weight loss pill.
How Is Forskolin Meant to Work? Forskolin has been studied as a potential weight-loss supplement because of the way it affects fat cells. In laboratory studies, forskolin causes fat cells to create more cAMP (cyclic Adenosine Monophosphate), a chemical messenger that leads to the breakdown of fat tissue. Since forskolin causes the breakdown of fat cells in a lab, it’s thought to perform the same in humans. That also remains unproven, however. Summary: Lab research has shown that forskolin causes breakdown of fat tissue. It’s still unknown whether or not this provides the same effect in the human body.
Does Forskolin Cause Weight-loss? Does Forskolin Cause Weight Loss?Even when forskolin does cause fat tissue to breakdown, that doesn’t really mean it will lead to weight-loss. Only two small research has looked at whether forskolin causes weight loss in humans. In a clinical trial of 15 obese men, one group was given 500 mg of 10% forskolin extract every day. After 12 weeks, your body fat percentages from the men taking forskolin decreased significantly – from around 35% to 31% – when compared with those given a placebo. Simultaneously, lean body weight in males taking forskolin increased by about 5%. However, while fat mass declined and lean body mass increased, total body weight failed to change.
Interestingly, the group taking forskolin also saw their testosterone levels increase, which can cause decreases in body fat. Researchers have not examined how or if perhaps forskolin might lead to testosterone levels to rise though. One other study found no influence on weight or body fat in 19 overweight women using the same dosage of forskolin.
Summary: Almost no research has been done on forskolin and weight-loss. One small study thought it was decreased unwanted fat and increased lean body weight in men, but with no overall weight change. Another study on women found no effect on weight or body composition.
Does Forskolin Prevent Putting On Weight? Does Forskolin Prevent Putting On Weight?Despite the fact that forskolin does not seem to cause weight loss, it may prevent putting on weight. In the second study cited above, overweight women who took forskolin gained less weight during the period of 12 weeks compared to those given a placebo. However, the differences were small. The average weight of ladies taking forskolin stayed approximately the same, whilst the average weight from the control group increased slightly (1.3 kg). The women failed to report any alternation in appetite. A study in rats also suggested that forskolin may prevent weight gain.
Researchers purposefully overfed rats so they would put on weight. The rats were separated into two groups – one received forskolin extract through the overfeeding period, the other failed to. People who received forskolin gained significantly less weight compared to other group – about 75% less. Additionally, they ate less food and their cholesterol levels improved significantly. While both of these studies show promising results, a lot more research is necessary to see whether forskolin extract can prevent putting on weight in humans. Summary: Two small reports have found that forskolin may help prevent weight gain. Far more research is necessary to confirm this influence on humans.
The 2 studies of forskolin and weight in humans did not find any negative health consequences. Cholesterol, insulin and blood pressure levels levels were not affected, without any significant side effects were reported. In those studies, 100-250 ml of any 10% forskolin extract was applied two times a day for 12 weeks. The consequences of utilizing an increased dosage or utilizing it for an extended time are unknown.
50 % of the nearly 1,300 reviews are 5 stars. Some people claimed to have achieved significant weight reduction, even within the first to 2 weeks of taking. Other positive results reported include: normalized bowels, decreased msvkiq and increased energy. Many reported weight reduction alongside diet and/or exercise (not only from the pill itself).
Some individuals saw no alternation in weight or overall health. Others experienced side effects like diarrhea, bloating, gas, and constipation. A couple of noted its contraindication with their blood pressure level medication.